MEDICAL INFORMATION FOR HEALTH CARE PROFESSIONALS

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MEGESTROL

Other names:  :   :  Megace

WHY is this medication prescribed ?

Megestrol is a medication similar to the hormone progesterone, which occurs naturally in the body.  Megestrol can improve appetite and promote weight gain when used together with an appropriate diet.

HOW should this drug be taken ?

Megestrol comes as a blue 40 mg tablet, a white 160 mg tablet, or as an oral suspension.  It is usually taken once or twice a day.  Since each person responds differently to medical treatments, your doctor will recommend the dose and duration of therapy that is best for you.

Megestrol can be taken with or without food.

What should you do if you FORGET a dose?

If you forget to take a dose, take it as soon as you remember, unless it is close to the time of the next dose. Do not double the dose, just carry on with your regular dosing schedule. Always check to make sure that the drug has not expired before using it.

What ADVERSE EFFECTS can this drug cause ? What should you do about them?

Mental excitation, difficulty concentrating, diarrhea, and flatulence  can occur.  Some people experience edema (swelling of the feet, ankles, and lower legs) or stomach upset.

These effects may go away during treatment as your body adjusts to the medicine.  However, check with your doctor if any of these effects continue or become bothersome.

Very rarely, long-term megestrol use may cause high blood sugar, impotence, or may affect your adrenal glands.

IT IS IMPORTANT THAT YOU KEEP YOUR DOCTOR AND LABORATORY APPOINTMENTS, SO THAT YOUR PROGRESS CAN BE ASSESSED REGULARLY.

IF YOU ARE EXPERIENCING ANY ADVERSE EFFECTS, PLEASE DISCUSS THEM WITH YOUR HEALTH CARE TEAM.

What other PRECAUTIONS should you follow while using this drug ?

Before beginning treatment with megestrol, make sure your doctor knows if:

  • you have any other illnesses besides HIV infection;
  • you are taking ANY other drugs (including those not prescribed by your doctor); or
  • you are pregnant, plan on becoming pregnant, or are breast-feeding a child.

 

This information will help you and your physician decide if the potential benefits of treating your condition with megestrol will outweigh the possible risks.

How should this medication be STORED?

Store megestrol at room temperature (2-30C). Do not store in your bathroom or kitchen as heat and moisture may cause the medication to lose its strength.

KEEP THIS AND ANY OTHER DRUGS OUT OF SIGHT AND OUT OF REACH FROM CHILDREN. DO NOT USE THIS MEDICINE AFTER THE EXPIRY DATE ("EXP") shown on the outside of the package.

IF YOU HAVE ANY QUESTIONS OR CONCERNS ABOUT THIS MEDICATION, PLEASE DISCUSS THEM WITH YOUR NURSE, PHARMACIST, OR PHYSICIAN.

PLEASE WRITE DOWN YOUR QUESTIONS OR CONCERNS TO ENSURE THEY ARE ADDRESSED

Adapted from Megace Product Monograph, Bristol Myers Squibb. Edited by the CSHP Ont. Branch Professional Specialty Group in HIV Disease in conjunction with the HIV/AIDS Outpatient Network Coordinators Sub-Group, 1997.