Children's Hospital of Eastern Ontario Department of Pharmacy
HIV PEDIATRIC HOSPITAL PHARMACY ELECTIVE ROTATION SITE
- Immunodeficiency Clinic, Children's Hospital of Eastern Ontario (CHEO)
- CHEO is a tertiary care pediatric facility serving the Eastern Ontario and Western Quebec regions with a catchment population of 1.5 million
- the clinic serves approximately 20 pediatric patients ranging from a few days old to under 18 years of age
- the medical team is comprised of HIV/infectious disease specialists, pediatric residents and fellows
- in addition, to medicine, the comprehensive interdisciplinary team comprises of nursing, pharmacy, social work, nutrition and the medical day unit
- ongoing clinical HIV research at CHEO presently involves phase III studies, open-label/expanded access, pharmacokinetics, and epidemiologic studies
DURATION OF ROTATION
PRECEPTOR
Natalie Dayneka, B.Sc.Phm., PharmD Clinical Specialist Pharmacy Department Children's Hospital of Eastern Ontario Telephone: 613-738-3622 Fax: 613-738-4206
E-mail: dayneka@cheo.on.ca pager: 239-7516
MEDICAL DIRECTOR OF HIV PROGRAM
Lindy Samson, M.D., FRCPC Division of Infectious Diseases Children's Hospital of Eastern Ontario Telephone: 613-737-2651
GOAL
The goal of this elective rotation is to familiarize the resident with basic pediatric pharmacokinetic and pharmacodynamic concepts as they relate to the pharmaceutical care of pediatric HIV patients.
OBJECTIVES
1. Through completion of assigned readings and discussion of therapeutic plans, the resident should be able to contrast pediatric pharmacology to adult pharmacology utilizing pharmacokinetic
principles, such as clearance and volume of distribution; and pharmacodynamic principles, such as dose response (altered sensitivity and tolerance). 2. By attending HIV clinic and following HIV
pediatric patients, the resident should be able to explain the differences between pediatric and adult HIV disease by utilizing differences in etiology, pathophysiology, signs, symptoms, and
complications of HIV. The resident should also be able to explain these differences as they relate to newborns, infants, children and adolescents. 3. The resident should be able to develop a
therapeutic plan for each pediatric age group, prioritize the potential adverse effects of each drug treatment, and demonstrate patient monitoring strategies for each drug treatment. 4. The
resident is to develop patient counselling strategies and demonstrate these strategies for each HIV drug treatment. These strategies are to accommodate the various pediatric age groups (newborns,
infants, children and adolescents). The ability to incorporate various patient adherence tools is to be demonstrated. 5. Utilizing pediatric drug dosage handbooks and pediatric drug
administration guidelines, the resident should be able to calculate an appropriate dose based on a patient's age, weight, and height; and interpret how to administer each medication. 6. Through a
case presentation to pharmacy staff, the resident is to demonstrate pediatric knowledge of a HIV topic. The provision of pharmaceutical care is also to be demonstrated by emphasizing how
drug-related problems were identified, solved and preventive strategy established. 7. Through participation in a pharmacy journal club, the resident is to demonstrate the ability to critically
appraise pediatric medical literature and highlight the differences (strengths/weaknesses) between adult and pediatric study designs. 8. The resident is to participate in pediatric HIV research
by completing a small project or a finite component of an ongoing CHEO HIV research project. The research project will be assigned under the guidance of the HIV Medical Director.
REQUIRED PREPARATORY READING
1. Centers for Disease Control and Prevention. Guidelines for the use of antiretroviral agents in pediatric HIV infection. MMWR 1198;47(No. RR-4):1-44.
HOUSING
CHEO pharmacy will assist the resident in finding housing; however, the selection and expense of housing will be the resident's responsibility.
CHEO House (available only to students/residents working at CHEO)
703 and 705 Smyth Road with 4 rooms on each side (one being a basement room). Private bedroom with desk. Linens supplied. Bring your own pillow. Shared bathroom, laundry facilities,
kitchen, living room, and dining room. Parking. 12 minute walk to hospital complex. On major bus route. $300/month, first come, first served basis.
Contact Pierre Leblanc, CHEO Security, at telephone number: 613-737-2227. Prepared by: Natalie Dayneka, B.Sc.Phm., PharmD
22 September 1998 |
