Reverse transcriptase synthesizes a double-stranded DNA copy of the single-stranded viral RNA generating a provirus.
Stage 5 - Integration (Figure 25)
The viral DNA migrates to and enters the host cell nucleus (a process facilitated by the HIV proteins vpr and MA) and
becomes integrated into the cell DNA with the help of the enzyme integrase. The provirus can then remain latent or be active, generating products for the generation of new virons.
