PPT Slide

Steady-State IDV Plasma Profile After IDV + RTV 400 mg Q12H With Food

E981561A 12

0.01

0.1

1

10

100

Indinavir Concentration (µg/mL)

0

4

8

12

16

20

24

Time (h)

IDV 800 mg q8h (Fasting)

IDV + RTV 400/400 mg q12h (regular 35%-fat meal)

IC90

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[Hsu et al. Antimicrob Agents Chemother 1998;42:2784-91].