MEDICAL INFORMATION FOR HEALTH CARE PROFESSIONALS

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FLUCONAZOLE

Other names: Diflucan ®

WHY is this medication prescribed?

Fluconazole is an antifungal medication. It is used to treat fungal infections in the mouth (like thrush), the esophagus, the genital tract (like a yeast infection) and other areas. It can also be used to prevent cryptococcal meningitis from recurring.

HOW should this drug be taken?

Take fluconazole for the duration of time it is prescribed. If you stop it earlier, your infection may come back. Keep appointments with your doctor and the laboratory so your response can be checked. The amount of drug to take depends on what is being treated. Your dosage is . Fluconazole can be taken with or without food.

What should you do if you FORGET a dose?

Take the missed dose as soon as you remember. If you remember your missed dose close to the time for your next dose just continue with your regular dosing schedule. Do not double your dose.

What ADVERSE EFFECTS can this drug cause? What should you do about them?

Generally, fluconazole is well tolerated by most people.

Fluconazole can increase liver enzymes. This usually does not give any symptoms. Rarely, hepatitis (an inflammation of the liver) can occur. Signs of this are yellowing of the eyes and skin, dark urine, pale stools, fatigue, and abdominal pain.

You may notice some stomach upset, nausea or vomiting while on fluconazole. Some other potential side effects are abdominal pain, diarrhea, headache and rash. If these effects occur, let the health care team know.

There are some other rare side effects from fluconazole. These include rash, lowering of white blood cells (cells that fight infection), and lowering of platelets (needed to help your blood clot). It is important to keep you appointments for regular blood work, so that any changes can be monitored.

What other PRECAUTIONS should you follow while using this drug?

Tell your physician or pharmacist what prescription or nonprescription medications you are currently taking. As well, before beginning any new prescription or nonprescription medications, discuss them with your physician or pharmacist.

The safety of fluconazole during pregnancy or breast feeding is not established. Please discuss this with your doctor or pharmacist if this is a concern.

How should this medication be STORED?

Fluconazole should be stored in a cool dry place, out of the reach of children. Keep this medication in the vial it was dispensed in. Do not store fluconazole or any other medication in the bathroom.

IF YOU HAVE ANY QUESTIONS OR CONCERNS ABOUT THIS MEDICATION, PLEASE DISCUSS THEM WITH YOUR PHARMACIST, NURSE, OR PHYSICIAN.

PLEASE WRITE DOWN YOUR QUESTIONS OR CONCERNS TO ENSURE THEY ARE ADDRESSED.

A pharmacist at ___________________ is available to answer questions.

The telephone number is ___________.  Please ask for ____________________.

 

Adapted from the Medication Teaching Manual, 6th ed. copyright 1994, American Society of Hospital Pharmacists, "Oral antifungal therapy" B.G.Hardy, Pharmacy Practice, Nov. 1994, DrugDex, Drug Evaluation Monograph.